--- title: "RADA16 use in Plastic surgery (facelift): a pilot study with an optimised application technique" description: "In the new publication “Facelift Patients Receiving Intraoperative Administration of a Self-assembling Haemostat Agent Experienced Minimal Bruising and No Acute Hematomas: A Pilot Study” (Aesthetic Surgery Journal, 2022) Dr Julius Few (US) reported his experience with the use of RADA16 (PuraSinus/PuraStat/PuraBond*) during Facelift procedures in patients with high risk of developing hematoma." image: https://news.3dmatrix.com/hubfs/FaceLiftImage_smaller.png --- ![](https://news.3dmatrix.com/hubfs/FaceLiftImage_smaller.png) # RADA16 use in Plastic surgery (facelift): a pilot study with an optimised application technique Published by [ 3-D Matrix ](https://news.3dmatrix.com/author/3-d-matrix) on Jun 27, 2022 10:00:00 AM The facelift is one of the most common cosmetic surgeries performed. Although the procedure is safe, it comes with the risk of complications such as hematoma formation (incidence from 1 to 9%)1, bruising, seroma, etc. Prevention of hematoma formation after facelift procedures represent an unmet need, especially for high-risk patients. In the new publication* “Facelift Patients Receiving Intraoperative Administration of a Self-assembling Hemostat Agent Experienced Minimal Bruising and No Acute Hematomas: A Pilot Study*”, (Few 2022)1 reported his experience with the use of RADA16 (PuraSinus/[PuraStat](https://3dmatrix.com/products/purastat/)/[PuraBond](https://3dmatrix.com/products/purabond/)*) during facelift procedures in patients with a high risk of developing a hematoma. The RADA16 hydrogel was applied intraoperatively prior to the skin closure with an **optimised procedure** well described in the paper. Postoperative follow-up for complications occurred on days 1, 3 and 7. **No acute haemorrhage **or** acute hematoma** were reported, and all patients had **minimal bruising or a dramatic absence of bruising.** The dramatic reduction of bruising in the patients reported in this case series and the ease of use has prompted the adoption of RADA16 as a standard of care in the senior author’s practice for all facelift procedures including patients at lower risk of haematoma. * PuraSinus/PuraStat/PuraBond are 2.5% synthetic aqueous RADA16 peptide solutions indicated in the US (FDA), UK (CE), UK (CE), respectively, for clinical use. RADA16 intraoperative application seems to have the potential **to deter acute hematoma and haemorrhage formation **and **to attenuate post-operative bruising** in facelift patients. Further investigation in a larger randomised controlled study is needed to confirm the data. To read the full article click [here](https://academic.oup.com/asjopenforum/article/doi/10.1093/asjof/ojac037/6576116).   1 Julius Few, MD, Facelift Patients Receiving Intraoperative Administration of a Self-assembling Hemostat Agent Experienced Minimal Bruising and No Acute Hematomas: A Pilot Study, Aesthetic Surgery Journal Open Forum, Volume 4, 2022, ojac037, https://doi.org/10.1093/asjof/ojac037 Tags: [3dmatrix](https://news.3dmatrix.com/tag/3dmatrix), [news](https://news.3dmatrix.com/tag/news), [US](https://news.3dmatrix.com/tag/us), [publication](https://news.3dmatrix.com/tag/publication), [corporate news](https://news.3dmatrix.com/tag/corporate-news), [purasinus](https://news.3dmatrix.com/tag/purasinus), [plastic surgery](https://news.3dmatrix.com/tag/plastic-surgery), [cosmetic](https://news.3dmatrix.com/tag/cosmetic), [RADA16](https://news.3dmatrix.com/tag/rada16) [Back to Blog](https://news.3dmatrix.com) ## Related Articles ## [A new multicentre study investigating PuraStat efficacy, safety, and ease of use for haemostasis in endonasal surgery (turbinate reduction, septoplasty and FESS).](https://news.3dmatrix.com/a-new-multicentre-study-investigating-purastat-efficacy-safety-and-ease-of-use-for-haemostasis-in-endonasal-surgery-turbinate-reduction-septoplasty-and-fess) Bleeding is a common intraoperative and/or post-operative issue in Endoscopic Endonasal Surgery... 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