---
title: "PuraStat reduces delayed bleeding after colorectal submucosal dissection: a new study presented at ESGE Days 2024"
description: 3-D Matrix announces the launch in the Spain market of PuraShield, a cutting-edge haemostatic agent for ENT surgical procedures.
---

[News ](https://news.3dmatrix.com)

# [PuraStat reduces delayed bleeding after colorectal submucosal dissection: a new study presented at ESGE Days 2024](https://news.3dmatrix.com/delayed-bleeding-after-colorectal-resection)

 Written by [3-D Matrix](https://news.3dmatrix.com/author/3-d-matrix) | Jun 28, 2024 9:30:00 AM

Delayed bleeding represents an important postoperative complication following endoscopic submucosal dissection (ESD).

Presented by L. Schmutte *et al*. at the ESGE Days 2024, this new retrospective study compared the delayed bleeding rate within 30 days after ESD with and without [**PuraStat**](https://3dmatrix.com/products/purastat/)’s application. In a cohort group of N=225 patients, N=108 (48%) received PuraStat after resection (1).

Below is shown the notable impact of [PuraStat](https://3dmatrix.com/products/purastat) application on delayed bleed rates, compared with the control group:

| Resection sites | Delayed Bleed Rates (%) |  |
| --- | --- | --- |
| With PuraStat | Without PuraStat |  |
| Colorectum | 7.14% | 18.2% |
| Oesophagus | 0% | 3.2% |

No adverse events related to PuraStat occurred. 

In conclusion, the study outcomes demonstrated that [PuraStat](https://3dmatrix.com/products/purastat)’s application after ESD can **significantly reduce the incidence of delayed bleeding**, particularly in the colorectum, highlighting its **safety and efficacy **(2).  

Click [**here**](https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0044-1782958) to read the full abstract.  

 

(1)  Schmutte, L., Ulrich, J., Wießner, J. R., Heilmaier, M., Schlag, C., & Abdelhafez, M. (2024). A self-assembling peptide reduces delayed bleeding after endoscopic submucosal dissection in the colorectum – a retrospective single center cohort study. Endoscopy. [https://doi.org/10.1055/s-0044-1782958](https://doi.org/10.1055/s-0044-1782958)

(2) [ PuraStat IFU 007-Rev 2; PuraStat IFU 011-Rev 2   
](https://news.3dmatrix.com/hubfs/2023%2c%20Adult%20tonsillectomy%2c%20Poste%20Baco%2c%20Dr%20Jo%20Stephens%2c%20PuraBond%20vs%20no%20treatment.pdf?_gl=1*acg46d*_ga*MzQ4NTAzNTIxLjE2NDU3OTAyMDk.*_ga_92W5LQ5EKN*MTcxMDUyMjc5MS4yNzcuMC4xNzEwNTIyNzk2LjU1LjAuMA..)

<https://news.3dmatrix.com/hubfs/2023%2c%20Adult%20tonsillectomy%2c%20Poste%20Baco%2c%20Dr%20Jo%20Stephens%2c%20PuraBond%20vs%20no%20treatment.pdf?_gl=1*acg46d*_ga*MzQ4NTAzNTIxLjE2NDU3OTAyMDk.*_ga_92W5LQ5EKN*MTcxMDUyMjc5MS4yNzcuMC4xNzEwNTIyNzk2LjU1LjAuMA..>

<https://news.3dmatrix.com/hubfs/2023%2c%20Adult%20tonsillectomy%2c%20Poste%20Baco%2c%20Dr%20Jo%20Stephens%2c%20PuraBond%20vs%20no%20treatment.pdf?_gl=1*acg46d*_ga*MzQ4NTAzNTIxLjE2NDU3OTAyMDk.*_ga_92W5LQ5EKN*MTcxMDUyMjc5MS4yNzcuMC4xNzEwNTIyNzk2LjU1LjAuMA..>

 

[View full post](https://news.3dmatrix.com/delayed-bleeding-after-colorectal-resection)

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